Table 2: The effect of various combinations of α-tocopherol (TC) and α-, δ-, and γ-tocotrienols (T3) on ACh-induced endothelium-dependent and SNP-induced endothelium-independent relaxation of rat aortae in the presence of pyrogallol- (P-) induced oxidative stress.

AChSNP
pEC50 (M) (%)pEC50 (M) (%)

Treatment
 Control6−7.20 ± 0.1593 ± 125−8.68 ± 0.1596 ± 2
 Pyrogallol5−6.77 ± 0.0750 ± 4#5−8.48 ± 0.09100 ± 2
 Pyrogallol + tocomin 10−4 mg/mL5−7.19 ± 0.1380 ±  5−8.34 ± 0.16105 ± 5
 P + T3 (α + δ + γ) + (α-TC) 10−4 mg/mL5−7.02 ± 0.1173 ±  4−8.49 ± 0.17102 ± 2
 P + T3 (α + γ) 10−4 mg/mL6−6.86 ± 0.2965 ± 6#5−8.20 ± 0.21102 ± 1
 P + T3 (α + δ + γ) 10−4 mg/mL3−6.57 ± 0.2361 ± 13#5−8.12 ± 0.08103 ± 2

Tocotrienol isomers and α-tocopherol were present in the proportions found in tocomin (i.e., is α-T3- 20%, δ-T3 10%, and γ-T3 50% and α-TC 20%).
#Significantly different to control .
Significantly different to pyrogallol .
Sidak’s multiple comparison test.