Research Article

Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer

Table 2

EC50 and maximum proapoptotic activity, expressed in percentage of apoptotic cells. Results were observed after 24 h (SW620) or 48 h (SW480) treatment with apple Pcys, lowbush blueberry, and lingonberry Pcy-rich extracts.

FruitHuman colon cancer cell line
SW620SW480SW620SW480
EC50 in µg/ml % of apoptotic cells at 75 µg/ml

Lowbush blueberry24.7 ± 0.125.2 ± 4.595 ± 1%92 ± 6%
Lingonberry24.3 ± 0.224.7 ± 0.137 ± 2%41 ± 5%
Apple 46.0 ± 4.534.6 ± 0.364 ± 9%55 ± 9%