Research Article

Enhancement of the Acrolein-Induced Production of Reactive Oxygen Species and Lung Injury by GADD34

Figure 2

Acrolein activates ER stress in lung tissue. Protein expression of ER stress was analyzed. Wild-type GADD34-knockout mice were intranasally instilled by 5 μmol/kg acrolein. Lung tissues were collected at the indicated times for western blot analysis.