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Oxidative Medicine and Cellular Longevity
Volume 2015, Article ID 197307, 9 pages
Research Article

Physical Activity, Aerobic Capacity, and Total Antioxidant Capacity in Healthy Men and in Men with Coronary Heart Disease

1Department of Geriatrics, Medical University of Lodz, Plac Hallera 1, 90-647 Lodz, Poland
2Department of Preventive Medicine, Medical University of Lodz, Żeligowskiego Street 7/9, 90-752 Lodz, Poland
3Department of Hygiene and Health Promotion, Medical University of Lodz, Jaracza Street 63, 90-251 Lodz, Poland
4Cardiac Rehabilitation Centre, Copernicus Memorial Hospital, Popioły Street 40, 93-438 Lodz, Poland
5Department of Physical Medicine, Medical University of Lodz, Plac Hallera 1, 90-647 Lodz, Poland
6Department of Clinical Physiology, Medical University of Lodz, Mazowiecka Street 6/8, 92-215 Lodz, Poland
7Department of Sports Medicine, Medical University of Lodz, Pomorska Street 251, 92-213 Lodz, Poland

Received 19 December 2014; Revised 15 February 2015; Accepted 24 February 2015

Academic Editor: Xinchun Pi

Copyright © 2015 Anna Gawron-Skarbek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The purpose of the study was to assess total antioxidant capacity (TAC) of blood serum in relation with habitual leisure time physical activity (LTPA) and aerobic capacity in a group of 90 men with coronary heart disease (CHD) aged 34.8–77.0 years and in 90 age-matched peers without CHD. Methods. Two spectrophotometric methods were applied to assess TAC: Ferric Reducing Ability of Serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH) tests. Aerobic capacity was expressed as physical working capacity at 85% of the maximal heart rate (). Results. CHD patients had higher values of TACFRAS ( versus  mmol FeCl2·L−1; ) but there were no group differences for TAC-DPPH and for uric acid (UA). Negative correlation was found between LTPA (also when calculated per kg of body mass) and TAC-DPPH in CHD patients. In CHD patients, TAC-FRAS and UA were lower in subjects with higher aerobic capacity expressed as . Those associations were not found in healthy men. Conclusions. We conclude that TAC of blood serum is moderately adversely related to LTPA and aerobic capacity in patients with CHD. UA, as the main determinant of serum TAC, may be partially responsible for those associations.