Heterogeneity of Systemic Oxidative Stress Profiles in COPD: A Potential Role of Gender

Table 5

Parameters associated with systemic lipid peroxidation in 54 patients with COPD (multivariate analysis: ANCOVA).

	Df	Sum Sq	Mean Sq	value	Pr (>)
Gender	1	421026	421026	7.46	0.01
Age (years)	1	53879	53879	0.96	0.33
Tobacco consumption (packs/year)	1	13984	13984	0.25	0.62
Physical activity level, Voorips score	1	48971	48971	0.87	0.36
Muscle mass index (Kg/m^2)	1	2134	2134	0.04	0.84
FEV1 (% pred.)	1	134549	134549	2.39	0.14
FEV1/FVC	1	17162	17162	0.31	0.59
6-MWD (% pred.)	1	291300	291300	5.18	0.03
Residuals	22	1239096	56323

To check parameters associated with systemic lipid peroxidation, we performed covariance analysis (ANCOVA). means that the parameter is statistically associated with systemic lipid peroxidation. COPD = chronic obstructive pulmonary disease; BMI = body mass index; FEV₁ = forced expiratory volume in 1 second; FVC = forced vital capacity; 6-MWD = 6-minute walking distance; Df = degrees of freedom; Sq = square.