Increased Oxidative Stress as a Selective Anticancer Therapy

Table 2

Anticancer therapies according to their different mechanisms in regulating ROS levels.

Mechanism	Therapy	Reference
Generation of ROS
Mitochondrial respiratory chain	Arsenic trioxide, anthracyclines (doxorubicin, daunorubicin, or epirubicin)	[172, 173]
NOX	Paclitaxel, ionizing radiation, niclosamide, AGX-891, AG-221	[174–178]
COX	Celecoxib	[179]
Elimination of ROS
GSH	Buthionine sulfoximine, sulfasalazine, NOV-002, 6-anicotinamide, l-asparaginase, small molecule 968	[180–186]
GSSH	Auranofin	[187]
Myeloperoxidase	Parthenolide	[188]