Smooth Muscle Specific Overexpression of p22phox Potentiates Carotid Artery Wall Thickening in Response to Injury
(a) Hematoxylin and eosin stained cross sections of carotid arteries harvested at selected time points following injury in C57BL/6J and mice. Representative sections from noninjured arteries ((A) and (B)) and carotid arteries 3 days after injury ((C) and (D)), 7 days after injury ((E) and (F)), and 14 days after injury ((G) and (H)) are shown. (b) Representative luminal images of fluo-4 treated sections of isolated carotid artery segments from a noninjured artery and injured arteries at days 0, 7, and 14 days following vascular injury. All images were obtained at a magnification of 200x and the scale bar is equal to 20 μm.
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