Chlorpyrifos Induces the Expression of the Epstein-Barr Virus Lytic Cycle Activator BZLF-1 via Reactive Oxygen Species

<div>Induction of BZLF-1 gene expression by CPF in Raji cells. Raji cells were stimulated with CPF, and the BZLF-1 gene expression level was evaluated by real-time PCR. (a) CPF induces the EBV lytic cycle through the expression of BZLF-1 in a dose-dependent manner. (b) Effect of the antioxidant NAC (50 <i>μ</i>M) on the CPF- (100 <i>μ</i>M) induced increase in BZLF-1 expression. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Chlorpyrifos Induces the Expression of the Epstein-Barr Virus Lytic Cycle Activator BZLF-1 via Reactive Oxygen Species 