Dexmedetomidine Attenuates Oxidative Stress Induced Lung Alveolar Epithelial Cell Apoptosis In Vitro

Figure 6

Possible molecular mechanism of Dex-mediated protection against oxidative stress in A549 cell death. H₂O₂-induced A549 cell death, cell cycle arrest, and loss of cellular adhesion, which was attenuated by Dex via inhibiting the ROS production. ↓ enhanced; ⊥ attenuated. Cas 3: caspase 3; Cas 9: caspase 9.