Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway

Figure 4

PI3K/Akt pathway was associated with polydatin-attenuated oxidative stress in renal I/R injury. Measurement of MDA (a), SOD (b), GST (c), GPx (d), CAT (e), and GSH (f) was performed on mice treated with different doses of polydatin and with or without wortmannin (1 mg/kg) at 3 d after I/R. versus sham; versus vehicle; versus polydatin (10 mg/kg); versus polydatin (20 mg/kg). versus control.

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