Resveratrol Derivative-Rich Melinjo Seed Extract Attenuates Skin Atrophy in Sod1-Deficient Mice

Figure 2

MSE and RSV attenuate collagen decline in skin tissues of Sod1^−/− mice. (a) Sirius red staining of the back skin of Sod1^−/− and Sod1^+/+ mice treated with the MSE or RSV. Relative mRNA expression of (b) Sirt1, (c) Col1a1, and (d) p53. Each of the mRNA expressions was determined by qRT-PCR ( 8–12). The statistical evaluations were performed using the two-tailed Student’s t-test for unpaired values. These data indicate the mean ± SD; , . The scale bar represents 100 μm.

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