Reactive Oxygen Species in Planarian Regeneration: An Upstream Necessity for Correct Patterning and Brain Formation

Figure 3

Relative gene expression levels of genes of interest; representing different classes (antioxidative, polarization-related, differentiation-related, proliferation-related, neuronal, and apoptosis-related genes). (a) Gene expression levels of DPI-exposed head fragments relative to the control group (0.01% DMSO) 4 hours post amputation (HPA). (b) Gene expression levels of DPI-exposed head fragments relative to the control group (0.01% DMSO) 72 hours post amputation (HPA). The values indicated in the graphs are the mean ± SEM of minimum 4 biological replicates. There was no effect of DMSO exposure on the expression levels of the measured genes. Significant effects (as compared to the corresponding 0.01% DMSO-exposed control worms): , . values were obtained via the Kruskal-Wallis test.

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