Thiosemicarbazone p-Substituted Acetophenone Derivatives Promote the Loss of Mitochondrial , GSH Depletion, and Death in K562 Cells
Reaction of TSC compounds with GSH. (a) Time-dependent bleaching of 10 M TSC-NO2 incubated with 20 M GSH in a nitrogen-equilibrated solution. (b) Time-dependent bleaching of 10 M TSC-NO2 incubated with 20 M GSH in an air-equilibrated solution. The inset of (a) shows the kinetics of TSC-Me (gray ball) and TSC-NO2 (black ball) bleaching at 304 and 340 nm, respectively, in nitrogen-equilibrated solutions.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.