Development of Antiatherosclerotic Drugs on the basis of Natural Products Using Cell Model Approach

Figure 3

Antiatherosclerotic effect of onion in ex vivo model. The study involved 4 volunteers (3 males, 1 female, mean age years) whose blood serum induced 1.3–1.5-fold increase in cholesterol content of cells cultured from unaffected human aortic intima (the average level of serum atherogenicity was %). Intracellular cholesterol in control cultures was  mg/mg cell protein. Baseline serum atherogenicity was taken as 100%. The average values of changes of serum atherogenicity with indication of standard errors are presented.