Xanthine Oxidase Inhibitor, Allopurinol, Prevented Oxidative Stress, Fibrosis, and Myocardial Damage in Isoproterenol Induced Aged Rats

Figure 3

Hematoxylin and Sosin staining showed inflammatory cell infiltration and necrosis in kidney section of rats treated with ISO. Sirius red staining showed fibrosis (red color) in kidney section of rats treated with ISO. (a, d) Control; (b, e) ISO; and (c, f) ISO + allopurinol, magnification 40x.

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