Treatment of β-Thalassemia/Hemoglobin E with Antioxidant Cocktails Results in Decreased Oxidative Stress, Increased Hemoglobin Concentration, and Improvement of the Hypercoagulable State
Table 1
Patient characteristics.
Curcuminoids cocktail
Vitamin E cocktail
Total
Responders
Non-responders
Total
Responders
Non-responders
Number of patients
25
16
9
25
19
6
Age (years)
32.5 ± 1.7
33.9 ± 2.5
30.1 ± 1.7
33.6 ± 2.1
33.0 ± 2.0
31.6 ± 4.3
Female : male,
14 : 11
7 : 9
7 : 2
19 : 6
13 : 5
6 : 1
Splenectomy,
11
7
4
9
6
3
Mean % change of serum ferritin at month 4 from baseline
−28.9
−39.7
+4.1
−33.5
−42.5
+4.7
Mean % change of RBC MDA at month 4 from baseline
−15.8
−24.2
−4.0
−30.1
−37.0
−5.4
The values represent mean ± standard error of the mean. MDA: malondialdehyde; RBC: red blood cells.
