Brewers’ Rice: A By-Product from Rice Processing Provides Natural Hepatorenal Protection in Azoxymethane-Induced Oxidative Stress in Rats

Figure 3

Histological characterization of liver tissue of rats from different experimental groups (magnification 200x). After eight weeks of treatment, normal group which received normal saline shows a mild fatty change within the hepatocytes (black arrow); AOM-only group shows a moderate inflammation and small localized inflammatory infiltrates (yellow arrow) surrounded by mild to moderate fatty changes (black arrow); dietary administration of 10% (w/w) brewers’ rice in the AOM-treated rats shows moderate inflammation (yellow arrow) and mild fatty changes (black arrow); dietary administration of 20% (w/w) brewers’ rice in the AOM-treated rats shows moderate fatty changes (black arrow); and dietary administration of 40% (w/w) brewers’ rice in the AOM-treated rats shows mild fatty changes (black arrow). After twenty weeks of treatment, normal group shows a mild fatty change within the hepatocytes (black arrow); AOM-only group shows a moderate inflammation and small localized inflammatory infiltrates (yellow arrow) surrounded by mild fatty changes (black arrow); dietary administration of 10% (w/w) brewers’ rice in the AOM-treated rats shows moderate inflammation (yellow arrow); dietary administration of 20% (w/w) brewers’ rice in the AOM-treated rats shows mild inflammation (yellow arrow); and dietary administration of 40% (w/w) brewers’ rice in the AOM-treated rats shows moderate fatty change (black arrow). Centrilobular vein (CV).