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Oxidative Medicine and Cellular Longevity
Volume 2015 (2015), Article ID 539798, 10 pages
http://dx.doi.org/10.1155/2015/539798
Research Article

Brewers’ Rice: A By-Product from Rice Processing Provides Natural Hepatorenal Protection in Azoxymethane-Induced Oxidative Stress in Rats

1Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
2Research Centre of Excellent, Nutrition and Non-Communicable Diseases (NNCD), Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
3Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
4Department of Pathology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
5Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
6Department of Food Technology, Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia

Received 31 March 2015; Accepted 30 June 2015

Academic Editor: Angel Catalá

Copyright © 2015 Bee Ling Tan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G.-J. Huang, J.-S. Deng, S.-S. Huang, Y.-Y. Shao, C.-C. Chen, and Y.-H. Kuo, “Protective effect of antrosterol from Antrodia camphorata submerged whole broth against carbon tetrachloride-induced acute liver injury in mice,” Food Chemistry, vol. 132, no. 2, pp. 709–716, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. V. R. L. López, G. S. Razzeto, M. S. Giménez, and N. L. Escudero, “Antioxidant properties of Amaranthus hypochondriacus seeds and their effect on the liver of alcohol-treated rats,” Plant Foods for Human Nutrition, vol. 66, no. 2, pp. 157–162, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Khurana, N. Shah, W. S. Twaddell et al., “S1880 divergent effects of M1 (M1r) and M3 (M3r) muscarinic receptor deletion in azoxymethane (AOM)-induced liver injury,” Gastroenterology, vol. 138, no. 5, supplement 1, pp. S-808–S-809, 2010. View at Publisher · View at Google Scholar
  4. C. H. F. Chan, D. Cook, and C. P. Stanners, “Increased colon tumor susceptibility in azoxymethane treated CEABAC transgenic mice,” Carcinogenesis, vol. 27, no. 9, pp. 1909–1916, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. J. M. Ward, R. S. Yamamoto, and C. A. Brown, “Pathology of intestinal neoplasms and other lesions in rats exposed to azoxymethane,” Journal of the National Cancer Institute, vol. 51, no. 3, pp. 1029–1039, 1973. View at Google Scholar · View at Scopus
  6. A. I. Cederbaum, Y. Lu, and D. Wu, “Role of oxidative stress in alcohol-induced liver injury,” Archives of Toxicology, vol. 83, no. 6, pp. 519–548, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Parola and G. Robino, “Oxidative stress-related molecules and liver fibrosis,” Journal of Hepatology, vol. 35, no. 2, pp. 297–306, 2001. View at Publisher · View at Google Scholar · View at Scopus
  8. H. A. El-Beshbishy, O. M. Tork, M. F. El-Bab, and M. A. Autifi, “Antioxidant and antiapoptotic effects of green tea polyphenols against azathioprine-induced liver injury in rats,” Pathophysiology, vol. 18, no. 2, pp. 125–135, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. J. Glatthar, J. J. Heinisch, and T. Senn, “The use of unmalted triticale in brewing and its effect on wort and beer quality,” Journal of the American Society of Brewing Chemists, vol. 61, no. 4, pp. 182–190, 2003. View at Google Scholar · View at Scopus
  10. N. M. Esa, T. B. Ling, and L. S. Peng, “By-products of rice processing: an overview of health benefits and applications,” Journal of Rice Research, vol. 1, no. 1, article 107, 2013. View at Google Scholar
  11. B. L. Tan, M. E. Norhaizan, S. K. Yeap, and K. Roselina, “Water extract of brewers' rice induces antiproliferation of human colorectal cancer (HT-29) cell lines via the induction of apoptosis,” European Review for Medical and Pharmacological Sciences, vol. 19, no. 6, pp. 1022–1029, 2015. View at Google Scholar
  12. B. L. Tan, M. E. Norhaizan, H. J. Suhaniza, C. C. Lai, S. Norazalina, and K. Roselina, “Antioxidant properties and antiproliferative effect of brewers' rice extract (temukut) on selected cancer cell lines,” International Food Research Journal, vol. 20, no. 5, pp. 2117–2124, 2013. View at Google Scholar · View at Scopus
  13. B. L. Tan, N. M. Esa, H. S. Rahman, H. Hamzah, and R. Karim, “Brewers' rice induces apoptosis in azoxymethane-induced colon carcinogenesis in rats via suppression of cell proliferation and the Wnt signaling pathway,” BMC Complementary and Alternative Medicine, vol. 14, article 304, 2014. View at Publisher · View at Google Scholar · View at Scopus
  14. R. P. Bird, “Aberrant crypt foci system to study cancer preventive agents in the colon,” in Tumor Marker Protocol, M. Hanausek and Z. Walaszek, Eds., pp. 465–474, Human Press, Totowa, NJ, USA, 1998. View at Google Scholar
  15. T.-J. Chiou, J. Zhang, V. J. Ferrans, and W.-F. Tzeng, “Cardiac and renal toxicity of menadione in rat,” Toxicology, vol. 124, no. 3, pp. 193–202, 1997. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Saravanan, N. Prakash Babu, P. Pandikumar, M. Karunai Raj, M. Gabriel Paulraj, and S. Ignacimuthu, “Immunomodulatory potential of Enicostema axillare (Lam.) A. Raynal, a traditional medicinal plant,” Journal of Ethnopharmacology, vol. 140, no. 2, pp. 239–246, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Boateng, M. Verghcse, V. Panala, L. T. Walker, and L. Shackelford, “Protective effects of rice bran on chemically induced colon tumorigenesis may be due to synergistic/additive properties of bioactive components,” International Journal of Cancer Research, vol. 5, no. 4, pp. 153–166, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. J. H. Chin, H. H. Abas, and I. Sabariah, “Toxicity study of Orthosiphon stamineus benth (misai kucing) on sprague dawley rats,” Tropical Biomedicine, vol. 25, no. 1, pp. 9–16, 2008. View at Google Scholar · View at Scopus
  19. R. Sallie, J. M. Tredger, and R. Williams, “Drugs and the liver part 1: testing liver function,” Biopharmaceutics and Drug Disposition, vol. 12, no. 4, pp. 251–259, 1991. View at Publisher · View at Google Scholar · View at Scopus
  20. J. El Hilaly, Z. H. Israili, and B. Lyoussi, “Acute and chronic toxicological studies of Ajuga iva in experimental animals,” Journal of Ethnopharmacology, vol. 91, no. 1, pp. 43–50, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. K. G. Tolman and R. Rej, “Liver function,” in Tietz Text Book of Clinical Chemistry, C. A. Burtis and and E. R. Ashwood, Eds., pp. 1125–1177, W.B. Saunders, Philadelphia, Pa, USA, 1999. View at Google Scholar
  22. M. H. Williams, Nutrition for Health, Fitness and Sport, McGraw-Hill, Boston, Mass, USA, 1999.
  23. B. Nordlinger, Y. Panis, J. P. Puts, J. P. Herve, R. Delelo, and F. Ballet, “Experimental model of colon cancer: recurrences after surgery alone or associated with intraperitoneal 5-fluorouracil chemotherapy,” Diseases of the Colon & Rectum, vol. 34, no. 8, pp. 658–663, 1991. View at Publisher · View at Google Scholar · View at Scopus
  24. D. Macejová and J. Brtko, “Chemically induced carcinogenesis: a comparison of 1-methyl-1-nitrosourea, 7,12-dimethylbenzanthracene, diethylnitroso-amine and azoxymethane models (minireview),” Endocrine Regulations, vol. 35, no. 1, pp. 53–59, 2001. View at Google Scholar · View at Scopus
  25. O. S. Sohn, E. S. Fiala, S. P. Requeijo, J. H. Weisburger, and F. J. Gonzalez, “Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol,” Cancer Research, vol. 61, no. 23, pp. 8435–8440, 2001. View at Google Scholar · View at Scopus
  26. S. M. O'Toole, A. E. Pegg, and J. A. Swenberg, “Repair of O6-methylguanine and O4-methylthymidine in F344 rat liver following treatment with 1,2-dimethylhydrazine and O6-benzylguanine,” Cancer Research, vol. 53, no. 17, pp. 3895–3898, 1993. View at Google Scholar · View at Scopus
  27. W. Liao, H. Wei, X. Wang et al., “Metabonomic variations associated with AOM-induced precancerous colorectal lesions and resveratrol treatment,” Journal of Proteome Research, vol. 11, no. 6, pp. 3436–3448, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. A. Gokcimen, K. Gulle, H. Demirin, D. Bayram, A. Kocak, and I. Altuntas, “Effects of diazinon at different doses on rat liver and pancreas tissues,” Pesticide Biochemistry and Physiology, vol. 87, no. 2, pp. 103–108, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. B. Fromenty and D. Pessayre, “Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity,” Pharmacology & Therapeutics, vol. 67, no. 1, pp. 101–154, 1995. View at Publisher · View at Google Scholar · View at Scopus
  30. N. Mohd Ali, H. Mohd Yusof, K. Long et al., “Antioxidant and hepatoprotective effect of aqueous extract of germinated and fermented mung bean on ethanol-mediated liver damage,” BioMed Research International, vol. 2013, Article ID 693613, 9 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  31. A. R. Humpage, S. J. Hardy, E. J. Moore, S. M. Froscio, and I. R. Falconer, “Microcystins (cyanobacterial toxins) in drinking water enhance the growth of aberrant crypt foci in the mouse colon,” Journal of Toxicology and Environmental Health—Part A, vol. 61, no. 3, pp. 155–165, 2000. View at Publisher · View at Google Scholar · View at Scopus
  32. R. C. Baybutt, C. Rosales, H. Brady, and A. Molteni, “Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats,” Toxicology, vol. 175, no. 1–3, pp. 1–13, 2002. View at Publisher · View at Google Scholar · View at Scopus
  33. S. K. Clinton, P. B. Imrey, H. J. Mangian, S. Nandkumar, and W. J. Visek, “The combined effects of dietary fat, protein, and energy intake on azoxymethane-induced intestinal and renal carcinogenesis,” Cancer Research, vol. 52, no. 4, pp. 857–865, 1992. View at Google Scholar · View at Scopus
  34. Y.-H. Kuo, P. Rozan, F. Lambein, J. Frias, and C. Vidal-Valverde, “Effects of different germination conditions on the contents of free protein and non-protein amino acids of commercial legumes,” Food Chemistry, vol. 86, no. 4, pp. 537–545, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. T. Norikura, A. Kojima-Yuasa, D. O. Kennedy, and I. Matsui-Yuasa, “Protective effect of gamma-aminobutyric acid (GABA) against cytotoxicity of ethanol in isolated rat hepatocytes involves modulations in cellular polyamine levels,” Amino Acids, vol. 32, no. 3, pp. 419–423, 2007. View at Publisher · View at Google Scholar · View at Scopus
  36. S. M. Watkins, L. C. Carter, J. Mak, J. Tsau, S. Yamamoto, and J. B. German, “Butyric acid and tributyrin induce apoptosis in human hepatic tumour cells,” Journal of Dairy Research, vol. 66, no. 4, pp. 559–567, 1999. View at Publisher · View at Google Scholar · View at Scopus
  37. Z. Xu, N. Hua, and J. S. Godber, “Antioxidant activity of tocopherols, tocotrienols, and γ-oryzanol components from rice bran against cholesterol oxidation accelerated by 2,2′-azobis(2-methylpropionamidine) dihydrochloride,” Journal of Agricultural and Food Chemistry, vol. 49, no. 4, pp. 2077–2081, 2001. View at Publisher · View at Google Scholar · View at Scopus
  38. T. Akihisa, K. Yasukawa, M. Yamaura et al., “Triterpene alcohol and sterol ferulates from rice bran and their anti- inflammatory effects,” Journal of Agricultural and Food Chemistry, vol. 48, no. 6, pp. 2313–2319, 2000. View at Publisher · View at Google Scholar · View at Scopus
  39. M. S. Islam, T. Murata, M. Fujisawa et al., “Anti-inflammatory effects of phytosteryl ferulates in colitis induced by dextran sulphate sodium in mice,” British Journal of Pharmacology, vol. 154, no. 4, pp. 812–824, 2008. View at Publisher · View at Google Scholar · View at Scopus
  40. R. Rodrigo and C. Bosco, “Oxidative stress and protective effects of polyphenols: comparative studies in human and rodent kidney. A review,” Comparative Biochemistry and Physiology C: Toxicology and Pharmacology, vol. 142, no. 3-4, pp. 317–327, 2006. View at Publisher · View at Google Scholar · View at Scopus