Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury

Figure 6

EDA inhibits caspase 3 activation in CGNs. CGNs were preincubated with or without EDA for 2 h followed by exposure to 50 μM IAA for another 4 h. Cells were lysed and caspase 3 activity was measured as described in Section 2.9. ^# versus control and ^** versus IAA alone group.