Transplanted Neural Stem Cells: Playing a Neuroprotective Role by Ceruloplasmin in the Substantia Nigra of PD Model Rats?

Figure 1

Influences of grafted NSCs on the TH-ir neurons in the SN of 6-OHDA-induced PD rats. (a, b) TH-ir neurons in control rats; (c, d) TH-ir cells in 6-OHDA-treated rats; (e, f) TH-ir neurons in NSCs-treated rats; (g, h, and i) the average total number of TH-ir neurons, Western blot, and real-time quantitative PCR in different groups: TH-ir neurons significantly decreased in the SN of 6-OHDA-treated rats compared with control rats (), while they increased in NSCs-treated rats compared with 6-OHDA-treated rats ().

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