Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits

Figure 1

Hind-limb function indicated a progressive decline in function of ischemia-reperfusion IR controls. The scores of Sham group at the same time point were higher than UTI + IR and IR groups (). The scores of hind-limb function in IR group declined from 4 h to 48 h, but rabbits treated with UTI (UTI + IR group) did not decline; their function stabilized and was significantly greater () than that in the IR controls at 24 h and 48 h after reperfusion. In UTI + IR group, function score was higher at 24 h and 48 h time points than at 4 h and 12 h time points (), but the score of IR group was higher at 4 h time point than at the other time points (). Values are the means ± SD, per group.