Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic β-Cell Damage

Figure 4

Nrf2-KD MIN6 cells are vulnerable to SNAP-induced cytotoxicity. (a) Following a 24 hr exposure to SNAP cell viability was assessed by MTT assay. (b) Immunoblotting of cleaved Caspase-3 (C-Casp-3), Caspase-3 (Casp-3), and cleaved PARP (C-PARP) in MIN6 cells exposed to SNAP for indicated time and concentrations. β-Actin was used as a loading control.

(a)

(b)