Regulation of MUTYH, a DNA Repair Enzyme, in Renal Proximal Tubular Epithelial Cells

Figure 1

Induced response to H₂O₂ and TGF-β1 in HK-2. Increased 8-oxoG staining was observed in HK-2 cells induced by H₂O₂ and TGF-β1 (a). Apoptotic cells with positive TUNEL staining increased after H₂O₂ treatment, but not after TGF-β1 treatment (b). Increased α-SMA expression and EMT in HK-2 cells was induced by TGF-β1, but not H₂O₂ (c).

(a)

(b)

(c)