Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

Figure 4

Venn diagram highlighting unique or shared DEGs during cellular senescence of the four human cell lines assayed. The numbers of differentially expressed genes ( value ≤ 0.05; FDR ≤ 0.1; F.C > 1.2) in HDFs (red frame); HSCs (blue frame); T-cells (green frame); and HMECs (purple frame) during cellular senescence are indicated. The two shaded intersections represent commonly regulated DEGs (respective genes are listed in each case) during cellular senescence of HDFs-HSCs-HMECs and of HDFs-HSCs-T-cells, respectively.