Research Article
Downregulation of Endogenous Hydrogen Sulfide Pathway Is Involved in Mitochondrion-Related Endothelial Cell Apoptosis Induced by High Salt
Figure 1
Changes in endogenous H2S pathway in human umbilical vein endothelial cells (HUVECs). (a) The concentration of endogenous H2S in supernatant detected by the free radical analyzer TBR4100; (b) the production of endogenous H2S in HUVEC determined by H2S fluorescent probe; and (c) CSE protein expression in HUVEC analyzed by western blotting. Control: the concentration of sodium was 137 mmol/L. HS: high salt; the concentration of sodium was 150 mmol/L, 200 mmol/L, and 250 mmol/L, respectively. The scale in (b) represented 20 μm. ; versus control group.
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