Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of Mito in Energy Homeostasis

Figure 4

Ontology and term enrichment of DEGs in Gene Ontology. (a–c): Ontology enrichment for Con versus A/R, A/R versus DZ, and DZ versus DZ5HD. Most of the DEGs from Con versus A/R (2056 DEGs, 48.86%), A/R versus DZ (2955, 50.2%), and DZ versus DZ5HD (2224, 49.59%) participated in the Biological Process ontology. (d–f): Histogram presentation of Gene Ontology functional classification and DEGs’ enrichment ((d) Con versus A/R; (e) A/R versus DZ; (f) DZ versus DZ5HD). The results are summarized in three main categories: Biological Process, Cellular Component, and Molecular Function. The -axis on the right is the number of DEGs in a category. The -axis on the left is the percentage of a specific category of genes in the main category. For significantly enriched terms (Con versus A/R, A/R versus DZ, and DZ versus DZ5HD), see Supplementary Tables 2–4.

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