Dry Olive Leaf Extract Counteracts L-Thyroxine-Induced Genotoxicity in Human Peripheral Blood Leukocytes In Vitro

Table 2

Posttreatment protocol: number of cells with damaged DNA from six different subjects, first treated with thyroxine and H₂O₂ and subsequently incubated with different concentrations of dry olive leaf extract (DOLE).

Oxidants		DOLE concentrations
		1 mg/mL	0.5 mg/mL	0.125 mg/mL
Thyroxine; (50 M)	16.67 ± 1.54	6.92 ± 1.2	3.58 ± 0.6	5.25 ± 0.7
H2O2 (25 M)	84.5 ± 4.93	16.83 ± 3.9	6.83 ± 2.7	14.5 ± 4.3

Values are expressed as mean ± SEM for comet scores in 100 cells from 6 subjects.
< 0.05 DOLE treatment versus oxidant, analyzed by one-way ANOVA test of variance.