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Oxidative Medicine and Cellular Longevity
Volume 2015, Article ID 787063, 8 pages
http://dx.doi.org/10.1155/2015/787063
Research Article

Exercise Training and Calorie Restriction Influence the Metabolic Parameters in Ovariectomized Female Rats

Department of Physiology, Anatomy and Neuroscience, University of Szeged, Kozep Fasor 52, Szeged 6726, Hungary

Received 16 July 2014; Accepted 15 September 2014

Academic Editor: Zsolt Radak

Copyright © 2015 Anikó Pósa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Maharlouei, N. Bellissimo, S. M. Ahmadi, and K. B. Lankarani, “Prevalence of metabolic syndrome in pre- and postmenopausal Iranian women,” Climacteric, vol. 16, no. 5, pp. 561–567, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. M. J. Toth, A. Tchernof, C. J. Rosen, D. E. Matthews, and E. T. Poehlman, “Regulation of protein metabolism in middle-aged, premenopausal women: roles of adiposity and estradiol,” The Journal of Clinical Endocrinology & Metabolism, vol. 85, no. 4, pp. 1382–1387, 2000. View at Publisher · View at Google Scholar · View at Scopus
  3. R. D. Leite, J. Prestes, C. F. Bernardes et al., “Effects of ovariectomy and resistance training on lipid content in skeletal muscle, liver, and heart; fat depots; and lipid profile,” Applied Physiology, Nutrition and Metabolism, vol. 34, no. 6, pp. 1079–1086, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. M. E. E. Jones, A. W. Thorburn, K. L. Britt et al., “Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 23, pp. 12735–12740, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. V. Beral, “Breast cancer and hormone-replacement therapy in the Million Women Study,” The Lancet, vol. 362, no. 9382, pp. 419–427, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Denis, L. Rochon, and Y. Deshaies, “Effects of exercise training on energy balance of ovariectomized rats,” The American Journal of Physiology—Regulatory Integrative and Comparative Physiology, vol. 253, no. 5, pp. R740–R745, 1987. View at Google Scholar · View at Scopus
  7. R. P. A. Barros and J.-Å. Gustafsson, “Estrogen receptors and the metabolic network,” Cell Metabolism, vol. 14, no. 3, pp. 289–299, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. F. Lizcano and G. Guzmán, “Estrogen deficiency and the origin of obesity during menopause,” BioMed Research International, vol. 2014, Article ID 757461, 11 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. J. C. Lovejoy, C. M. Champagne, L. de Jonge, H. Xie, and S. R. Smith, “Increased visceral fat and decreased energy expenditure during the menopausal transition,” International Journal of Obesity, vol. 32, no. 6, pp. 949–958, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. N. H. Rogers, J. W. P. Li, K. J. Strissel, M. S. Obin, and A. S. Greenberg, “Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity,” Endocrinology, vol. 150, no. 5, pp. 2161–2168, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Hao, Y. Wang, Y. Duan, and S. Bu, “Effects of treadmill exercise training on liver fat accumulation and estrogen receptor α expression in intact and ovariectomized rats with or without estrogen replacement treatment,” European Journal of Applied Physiology, vol. 109, no. 5, pp. 879–886, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. I. Cameron, M. A. Alam, J. Wang, and L. Brown, “Endurance exercise in a rat model of metabolic syndrome,” Canadian Journal of Physiology and Pharmacology, vol. 90, no. 11, pp. 1490–1497, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. C. Cornelius, R. Perrotta, A. Graziano, E. J. Calabrese, and V. Calabrese, “Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: mitochondria as a ‘chi’,” Immunity and Ageing, vol. 10, no. 1, article 15, 2013. View at Publisher · View at Google Scholar · View at Scopus
  14. V. Calabrese, C. Cornelius, S. Cuzzocrea, I. Iavicoli, E. Rizzarelli, and E. J. Calabrese, “Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity,” Molecular Aspects of Medicine, vol. 32, no. 4–6, pp. 279–304, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. E. C. Paulino, J. C. Batista Ferreira, L. R. Bechara et al., “Exercise training and caloric restriction prevent reduction in cardiac Ca2+-handling protein profile in obese rats,” Hypertension, vol. 56, no. 4, pp. 629–635, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Kang, K. B. Kim, and K. O. Shin, “Exercise training improves leptin sensitivity in peripheral tissue of obese rats,” Biochemical and Biophysical Research Communications, vol. 435, no. 3, pp. 454–459, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. R. D. Leite, R. D. C. M. Durigan, A. D. De Souza Lino et al., “Resistance training may concomitantly benefit body composition, blood pressure and muscle MMP-2 activity on the left ventricle of high-fat fed diet rats,” Metabolism: Clinical and Experimental, vol. 62, no. 10, pp. 1477–1484, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. F. Meziri, D. Binda, S. Touati et al., “Exercise aggravates cardiovascular risks and mortality in rats with disrupted nitric oxide pathway and treated with recombinant human erythropoietin,” European Journal of Applied Physiology, vol. 111, no. 8, pp. 1929–1938, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Touati, F. Meziri, S. Devaux, A. Berthelot, R. M. Touyz, and P. Laurant, “Exercise reverses metabolic syndrome in high-fat diet-induced obese rats,” Medicine and Science in Sports and Exercise, vol. 43, no. 3, pp. 398–407, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. P. W. Endlich, E. R. G. Claudio, W. L. da Silv Goncalves, S. A. Gouvêa, M. R. Moysés, and G. R. de Abreu, “Swimming training prevents fat deposition and decreases angiotensin II-induced coronary vasoconstriction in ovariectomized rats,” Peptides, vol. 47, pp. 29–35, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. E. R. G. Claudio, P. W. Endlich, R. L. Santos et al., “Effects of chronic swimming training and oestrogen therapy on coronary vascular reactivity and expression of antioxidant enzymes in ovariectomized rats,” PLoS ONE, vol. 8, no. 6, Article ID e64806, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. S. J. Lessard, D. A. Rivas, Z.-P. Chen et al., “Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance,” Diabetes, vol. 56, no. 7, pp. 1856–1864, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. C. R. Bruce, A. B. Thrush, V. A. Mertz et al., “Endurance training in obese humans improves glucose tolerance and mitochondrial fatty acid oxidation and alters muscle lipid content,” The American Journal of Physiology—Endocrinology and Metabolism, vol. 291, no. 1, pp. E99–E107, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. J. P. G. Camporez, F. R. Jornayvaz, H.-Y. Lee et al., “Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance,” Endocrinology, vol. 154, no. 3, pp. 1021–1028, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. J. M. Friedman, “Leptin at 14 y of age: an ongoing story,” The American Journal of Clinical Nutrition, vol. 89, no. 3, pp. 973S–979S, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. M. B. S. Flores, M. F. A. Fernandes, E. R. Ropelle et al., “Exercise improves insulin and leptin sensitivity in hypothalamus of wistar rats,” Diabetes, vol. 55, no. 9, pp. 2554–2561, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. E. Riant, A. Waget, H. Cogo, J.-F. Arnal, R. Burcelin, and P. Gourdy, “Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice,” Endocrinology, vol. 150, no. 5, pp. 2109–2117, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. A. S. Gami, B. J. Witt, D. E. Howard et al., “Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies,” Journal of the American College of Cardiology, vol. 49, no. 4, pp. 403–414, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. N. Zoth, C. Weigt, U. Laudenbach-Leschowski, and P. Diel, “Physical activity and estrogen treatment reduce visceral body fat and serum levels of leptin in an additive manner in a diet induced animal model of obesity,” The Journal of Steroid Biochemistry and Molecular Biology, vol. 122, no. 1–3, pp. 100–105, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. M. L. Mestek, E. Plaisance, and P. Grandjean, “The relationship between pedometer-determined and self-reported physical activity and body composition variables in college-aged men and women,” Journal of American College Health, vol. 57, no. 1, pp. 39–44, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Pósa, K. Kupai, R. Ménesi et al., “Sexual dimorphism of cardiovascular ischemia susceptibility is mediated by heme oxygenase,” Oxidative Medicine and Cellular Longevity, vol. 2013, Article ID 521563, 11 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. Z. Szalai, A. Szász, I. Nagy et al., “Anti-inflammatory effect of recreational exercise in TNBS-Induced colitis in rats: role of NOS/HO/MPO system,” Oxidative Medicine and Cellular Longevity, vol. 2014, Article ID 925981, 11 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. J. M. Friedman and J. L. Halaas, “Leptin and the regulation of body weight in mammals,” Nature, vol. 395, no. 6704, pp. 763–770, 1998. View at Publisher · View at Google Scholar · View at Scopus
  34. Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold, and J. M. Friedman, “Positional cloning of the mouse obese gene and its human homologue,” Nature, vol. 372, pp. 425–432, 1994. View at Publisher · View at Google Scholar
  35. K. El-Haschimi, D. D. Pierroz, S. M. Hileman, C. Bjørbæk, and J. S. Flier, “Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity,” The Journal of Clinical Investigation, vol. 105, no. 12, pp. 1827–1832, 2000. View at Publisher · View at Google Scholar · View at Scopus
  36. Y. Han, Y. Joe, E. Seo et al., “The hyperleptinemia and ObRb expression in hyperphagic obese rats,” Biochemical and Biophysical Research Communications, vol. 394, no. 1, pp. 70–74, 2010. View at Publisher · View at Google Scholar · View at Scopus
  37. I. Shimokawa and Y. Higami, “Leptin signaling and aging: insight from caloric restriction,” Mechanisms of Ageing and Development, vol. 122, no. 14, pp. 1511–1519, 2001. View at Publisher · View at Google Scholar · View at Scopus
  38. I. Shimokawa and Y. Higami, “Leptin and anti-aging action of caloric restriction,” The Journal of Nutrition, Health and Aging, vol. 5, no. 1, pp. 43–48, 2001. View at Google Scholar · View at Scopus
  39. M. Mainardi, G. Scabia, T. Vottari et al., “A sensitive period for environmental regulation of eating behavior and leptin sensitivity,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 38, pp. 16673–16678, 2010. View at Publisher · View at Google Scholar · View at Scopus
  40. A. J. G. Hanley, K. Williams, A. Festa, L. E. Wagenknecht, R. B. D'Agostino Jr., and S. M. Haffner, “Liver markers and development of the metabolic syndrome: the Insulin Resistance Atherosclerosis Study,” Diabetes, vol. 54, no. 11, pp. 3140–3147, 2005. View at Publisher · View at Google Scholar · View at Scopus
  41. C. S. Lieber, M. A. Leo, K. M. Mak et al., “Model of nonalcoholic steatohepatitis,” The American Journal of Clinical Nutrition, vol. 79, no. 3, pp. 502–509, 2004. View at Google Scholar · View at Scopus
  42. U. G. M. de Castro, R. A. S. dos Santos, M. E. Silva, W. G. de Lima, M. J. Campagnole-Santos, and A. C. Alzamora, “Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats,” Lipids in Health and Disease, vol. 12, no. 1, article 136, 2013. View at Publisher · View at Google Scholar · View at Scopus