The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells

Figure 4

The effects of RNSP on H₂O₂-medicated MAPKs activation in SH-SY5Y cells. (a) The phosphorylation of p38 in H₂O₂-exposed cells with or without RNSP (60 μg/mL, 2 h). (b) The quantitative analyses of the immunoblotting from (a). Each column and bar represent the mean ± SEM (, each). An asterisk indicates a statistically significant difference from the value in the untreated cells (, ). Pound signs indicate a statistically significant difference from the value in H₂O₂-exposed cells without RNSP (^###). (c) The phosphorylation of pERK1/2 in H₂O₂-exposed cells with or without RNSP (60 μg/mL, 2 h). (d) The quantitative analyses of the immunoblotting in (c). Each column and bar represent the mean ± SEM ( each). Asterisks indicate a statistically significant difference from the value in untreated cells (). Pound signs indicate a statistically significant difference from the value in the H₂O₂-exposed cells without RNSP (^###).

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