Association of Age-Related Macular Degeneration with Erythrocyte Antioxidant Enzymes Activity and Serum Total Antioxidant Status

Table 3

Prediction of AMD based on the combined erythrocyte GPx activity and serum TAS value.

	AMD; ()	Control; ()	Predictive value
At least one bellow the cut-off^*	54 (94.7)	24 (48.0)	Positive; 0.69 (0.63–0.72)
Both TAS and GPx above the cut-off	3 (5.3)	26 (52.0)	Negative; 0.90 (0.74–0.97)
Total	57 (100.0)	50 (100.0)
	Sensitivity; 0.95 (0.87–0.99)	Specificity; 0.52 (0.43–0.56)

Values are presented as (%).
AMD = age-related macular degeneration; TAS = serum total antioxidant status index; GPx = glutathione peroxidase.
Cut-off values were set up based on the Youden index , ≤1.44 for TAS, ≤48.97 for GPx.