Research Article

Rimonabant Improves Oxidative/Nitrosative Stress in Mice with Nonalcoholic Fatty Liver Disease

Table 2

The effect of rimonabant on concentration of oligoelements in the liver.

Groups Concentration of oligoelements (mg/kg)
Fe Zn Mg Cu

C82.90 ± 4.8336.69 ± 5.021.27 ± 0.012.66 ± 0.15
R88.09 ± 6.2245.79 ± 6.160.06 ± 0.014.04 ± 0.48
HF110.59 ± 10.0729.10 ± 2.382.41 ± 0.234.33 ± 0.24
HFR70.46 ± 10.07##50.10 ± 8.65##10.01 ± 1.99##5.53 ± 1.38##

Fe—iron; Zn—zinc; Mg—manganese; Cu—copper.
C-control group fed with control chow diet for 20 weeks; R-group fed with standard chow diet and treated with rimonabant after 18 weeks; HF-group fed with high saturated fat diet for 20 weeks; HFR- group fed with high saturated fat diet and treated with rimonabant after 18 weeks.
Significance of the difference was estimated by using one-way analysis of variance (ANOVA) with Tukey’s post hoc test (, vs. C, and vs. HF).