Coenzyme Q10 Inhibits the Aging of Mesenchymal Stem Cells Induced by D-Galactose through Akt/mTOR Signaling

Figure 2

Effects of different concentrations CoQ10 on MSCs senescence induced by D-gal. (a) SA-β-gal staining. In the 10 μmol/L CoQ10 and the 100 mol/L CoQ10 groups, the number of SA-β-gal-positive cells was clearly decreased compared with that in the D-gal control group. Scale bar = 25 μm. (b) Quantification of SA-β-gal-positive cells. The total number of SA-β-gal-positive cells among 100 random cells was counted using phase-contrast microscopy. The results showed that the number of SA-β-gal-positive MSCs/100 cells in the 10 μmol/L CoQ10 and the 100 μmol/L CoQ10 groups was significantly lower than that in the D-gal control group (; ).

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