Oxidative Medicine and Cellular Longevity / 2015 / Article / Tab 2

Research Article

Flaxseed Oil Containing α-Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice

Table 2

Effects of FO+ALA-PS on lipid profiles in mice.

Groups
ControlHFD FOFO+ALA-PS

Serum TC (mmol/L)1.72 ± 0.24 20.77 ± 5.00a16.04 ± 4.59a11.33 ± 3.15abc
Serum TG (mmol/L) 0.91 ± 0.15 2.27 ± 0.40a1.83 ± 0.42ab1.39 ± 0.41abc
Serum LDL-C (mmol/L) 0.31 ± 0.12 12.16 ± 3.11a10.24 ± 2.32a4.17 ± 1.35abc
Serum HDL-C (mmol/L)1.01 ± 0.14 0.26 ± 0.12a0.45 ± 0.23ab0.60 ± 0.16abc
Liver TC (mg/g) 2.54 ± 0.19 4.09 ± 0.75a3.52 ± 0.38a2.55 ± 0.24bc
Liver TG (mg/g) 26.47 ± 6.40 64.04 ± 18.49a40.81 ± 7.63ab30.80 ± 6.21bc

Forty-two apoE KO mice were randomly divided into 3 groups on average, namely, HFD, FO, and FO+ALA-PS. Fourteen wild type C57BL/6 mice were divided into control group. Values are given as means ± SD (). a < 0.05 versus the control; b < 0.05 versus the HFD group; c < 0.05 versus the FO group. HFD: high fat diet; FO: HFD + 5% flaxseed oil; FO + ALA-PS: HFD + 2.7% flaxseed oil + 3.3% flaxseed oil ester of plant sterol.

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.