The Nutraceutical Dehydrozingerone and Its Dimer Counteract Inflammation- and Oxidative Stress-Induced Dysfunction of In Vitro Cultured Human Endothelial Cells: A Novel Perspective for the Prevention and Therapy of Atherosclerosis

Figure 7

Tissue factor (TF) expression and nuclear factor-κB activation. (a) shows the detection of TF expression on cell membrane in HUVEC pretreated with DHZ or DHZ dimer and then treated with TNF-α 10 ng/mL for 6 hours (mean values of four experiments). (b) shows the evaluation of p50 (i) and p65 (ii) translocation within the nucleus in HUVEC pretreated with DHZ or DHZ dimer and then treated with TNF-α 10 ng/mL for 1 hour (mean values of four experiments). Error bars represent SD. (a) ; . (b) (i) and (ii) ; ; a.u.: arbitrary units.

(a)

(b)