Oxidative Medicine and Cellular Longevity

Research Article

Upregulation of Heme Oxygenase-1 in Response to Wild Thyme Treatment Protects against Hypertension and Oxidative Stress

Table 1

The correlation between haemodynamic parameters and oxidative status in hypertensive () and normotensive rats ().

⁢L-TBARS

⁢p-TBARS

⁢k-TBARS

⁢L-HO-1

⁢p-HO-1

⁢BIL-D

⁢BIL-T

SHR

MAP

0.2830
= 0.373

−0.7060
= 0.010

−0.0489
= 0.880

0.6251
= 0.030

0.2371
= 0.458

−0.1796
= 0.577

0.4435
= 0.149

−0.6159
= 0.033

−0.4965
= 0.101

−0.3846
= 0.217

−0.3628
= 0.246

−0.9249
= 0.000

0.4006
= 0.197

−0.6398
= 0.025

TPVR

−0.1109
= 0.732

−0.7578
= 0.004

−0.1013
= 0.754

0.4923
= 0.104

0.3308
= 0.294

−0.0962
= 0.766

0.3023
= 0.340

−0.4951
= 0.102

0.1118
= 0.730

−0.6518
= 0.022

−0.5295
= 0.077

−0.7001
= 0.011

0.2704
= 0.395

−0.4377
= 0.155

SHR: spontaneously hypertensive rats that received vehicle or thyme extract; W: Wistar rats that received vehicle or thyme extract; MAP: mean arterial pressure; TPVR: total peripheral vascular resistance; L-TBARS, p-TBARS, and k-TBARS: liver thiobarbituric acid reactive substance, plasma thiobarbituric acid reactive substance, and kidney thiobarbituric acid reactive substances; quantity of L-HO-1 and p-HO-1: liver and plasma heme oxigenase-1 enzyme; BIL-D: direct bilirubin; BIL-T: total bilirubin. Marked correlations are significant at < 0.050.