Upregulation of Heme Oxygenase-1 in Response to Wild Thyme Treatment Protects against Hypertension and Oxidative Stress

Table 2

The correlation of oxidative stress parameters with heme oxigenase-1 expression and activity in hypertensive () and normotensive rats ().

	⁢L-HO-1		⁢HO-1		⁢BIL-D		⁢BIL-T
	W	SHR	W	SHR	W	SHR	W	SHR
L-TBARS	0.0775; = 0.811	0.6284; = 0.029	−0.1981; = 0.537	0.6444; = 0.024	0.0034; = 0.992	0.7475; = 0.005	0.2548; = 0.424	0.5980; = 0.040
p-TBARS	−0.2623; = 0.410	−0.7715; = 0.003	−0.0377; = 0.908	−0.3397; = 0.280	0.0890; = 0.783	−0.7623; = 0.004	0.0614; = 0.850	−0.5674; = 0.054
k-TBARS	0.6801; = 0.015	0.4457; = 0.147	0.1703; = 0.597	0.4521; = 0.140	−0.4280; = 0.165	0.0775; = 0.811	0.2146; = 0.503	0.4398; = 0.153

SHR: spontaneously hypertensive rats that received vehicle or thyme extract; W: Wistar rats that received vehicle or thyme extract; L-TBARS, p-TBARS, and k-TBARS: liver thiobarbituric acid reactive substance, plasma thiobarbituric acid reactive substance, and kidney thiobarbituric acid reactive substances; quantity of L-HO-1 and p-HO-1: liver and plasma heme oxigenase-1 enzyme; BIL-D: direct bilirubin; BIL-T: total bilirubin. Marked correlations are significant at < 0.050.