Berberine Attenuates Myocardial Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Inflammation Response: Role of Silent Information Regulator 1

Figure 3

Effects of berberine and sirtinol treatment on inflammation response in normal rat heart. Normal SD rats treated with BBR (200 mg/kg/d for 2 weeks) or Stnl (2 mg/kg/d for 1 week) were subjected to Sham operation. Inflammation markers were measured 6 hr after the surgery. (a) Myocardium IL-6 level. (b) Myocardium TNF-α level. (c) Serum TNF-α level. (d) Myocardium MPO activity. The results are expressed as the mean ± SEM, /group.

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