Research Article
C1q/TNF-Related Protein 9 Protects Diabetic Rat Heart against Ischemia Reperfusion Injury: Role of Endoplasmic Reticulum Stress
Table 2
CTRP9 protected diabetic hearts against IR injury.
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Isolated hearts from diabetic rats were subjected to IR or control protocol via a Langendorff apparatus at the presence of different dosage of globular CTRP9 (0.3, 1, and 3 μg/mL for IR+0.3, IR+1, and IR+3 groups, resp.) or equal amount of KH buffer (control), and heart rate (HR), coronary flow (CF), left ventricular developing pressure (LVDP), maximum and minimum electronically differentiated derivative of left ventricular pressure (±dP/dt) and rate-pressure product (RPP) were compared at the end of reperfusion (120 min). , versus control, , versus IR, , versus IR+0.3, and per group. |