Phytochemical Composition, Antioxidant Activity, and the Effect of the Aqueous Extract of Coffee (Coffea arabica L.) Bean Residual Press Cake on the Skin Wound Healing

Table 5

Wound area size (cm²) in the elapsing time of 15 days, with daily application of green coffee press cake and chlorogenic acid hydrogels.

Groups ()	Day 0	Day 3	Day 7	Day 15
GC	0.70 ± 0.02 a	0.75 ± 0.06 ab	0.42 ± 0.04 a	0.002 ± 0.02 a
CGA	0.70 ± 0.02 a	0.57 ± 0.02 a	0.41 ± 0.02 a	0.002 ± 0.02 a
PC	0.72 ± 0.02 a	0.55 ± 0.06 a	0.31 ± 0.04 a	0.00 ± 0.01 a
NC	0.74 ± 0.02 a	0.85 ± 0.06 b	0.42 ± 0.04 a	0.002 ± 0.02 a

Data are presented as means ± sem. Distinct letters in the column denote significant differences (Tukey test, ). GC = green coffee, CGA = chlorogenic acid, PC = positive control, and CN = negative control.