Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice

Table 1

Chromosome aberrations in bone marrow cells from LDLTR radiated mice.

Dose (Gy)	Treatment	TCC	TAM	TAC	Fragments		Gaps		Dicentrics		RT	DLE	EX	ACR (%)
					CMT	CTT	CMT	CTT	CMT	CTT				Mean	SD
.0	Nonhydrogen	828	144	148	84	18	12	16	4	6	6	0	2	17.420	3.097
	Hydrogen	842	146	148	84	12	4	14	14	10	10	0	0	17.380	1.731
.1	Nonhydrogen	848	164	164	98	22	14	12	4	10	2	2	0	19.349	1.758
	Hydrogen	852	152	154	108	16	8	8	8	4	2	0	0	17.865	2.852
.5	Nonhydrogen	898	192	192	130	26	10	4	18	6	2	2	0	21.390	4.122
	Hydrogen	840	144	146	78	20	8	16	10	8	6	0	0	17.117	1.135
1.0	Nonhydrogen	826	192	198	104	28	14	26	4	12	6	2	2	23.222	1.038
	Hydrogen	830	152	154	70	32	4	12	6	12	18	0	0	18.286	2.016
2.0	Nonhydrogen	834	296	298	170	50	18	16	20	8	16	0	0	35.485	3.298
	Hydrogen	858	244	244	134	22	8	30	10	26	8	4	2	28.350	3.207

All sorts of CAs are scored and displayed here. In each group, eight mice were included for this evaluation, with at least 100 metaphases examined for each of them (). Dose: radiation doses exposed to animals; treatment: whether treating the subjects with hydrogen or not; TCC: total counted cells. TAM: total aberrant metaphases. TAC: total aberrant chromosomes. CMT: chromosomal type; CTT: chromatid type. RT: Robertsonian translocation. DEL: deletion. EX: exchange.
Aberrant cells rate were compared with the method of two-way ANOVA. As for the radiation factor, and ; hydrogen: and . Furthermore, there existed statistically interaction between radiation and hydrogen treatment (, ). The LSD-test was selected for the subsequent comparisons between each radiation dose group.
The aberrant cells rates of groups that have totally different superscripts are significantly different from each other ( as significant, SNK test was used here).