Review Article

New Insights into the Role of Oxidative Stress Mechanisms in the Pathophysiology and Treatment of Multiple Sclerosis

Table 2

The types of antioxidants. The types of antioxidants depend on molecular structure. The table lists the most important barrier antioxidant enzymes and other compounds and ions which are not enzymes.

Enzymes oxidants [16, 29, 4144]Nonenzymatic antioxidants [13]
Low molecular weight antioxidants Antioxidant elements

CAT
GPx
GR
SOD
Paraoxonase
Arylesterase
GSTs
NQO1
Peroxiredoxin-3
Thioredoxin-2, 6
FeOx
δ-ALA-D
Uric acid
Vitamin C
Vitamin D
Vitamin E
Glutathione
Coenzyme Q
B-Carotene
AU
Ions: Cu, Fe, Zn, Mn

CAT: catalase, GPx: glutathione peroxidase, GR: glutathione reductase, SOD: superoxide dismutase, GSTs: glutathione-S-transferases, NQO1: NAD(P)H:quinone oxidoreductase 1, FeOx: ferroxidase, δ-ALA-D: δ aminolevulinate dehydratase, and AU: uric acid.