Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome Activation with Mitophagy

Figure 6

To investigate the mitophagy in the myocardium, the expressions of several mitochondrial autophagy-related proteins were examined. Compared with that of the RC group, the expressions of Beclin1, Bnip3, and total LC3, as well as the ratio of LC3 II to LC3 I, were all increased during the early stages of both acute exercise and its recovery ((a), (b), (c), and (d)). Each bar represents the mean ± SEM of a treatment group (). and versus RC group.

(a)

(b)

(c)

(d)