Aging Increases Susceptibility to High Fat Diet-Induced Metabolic Syndrome in C57BL/6 Mice: Improvement in Glycemic and Lipid Profile after Antioxidant Therapy

Figure 1

Body weight and WAT index. Monitoring of body weight (g) during the weeks before and after pharmacological intervention with tempol (50 mgkg⁻¹) and apocynin (50 mgkg⁻¹) in young (a) and old (c) C57BL/6 mice. WAT index (%) and representative pictures of the HF diet animals after pharmacological intervention in young (b) and old (d) C57BL/6 mice. CT = control group; HF = high fat diet group; HFT = high fat diet + tempol group; HFA = high fat diet + apocynin group. Each point of the graph represents the mean ± SEM. ANOVA (two-way) with Bonferroni’s post hoc test: ; ; , CT versus HF. Each bar graph represents the mean ± SEM. ANOVA (one-way) with Bonferroni’s post hoc test: , CT versus HF ( = 5-6).

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