Hydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway
Effect of H2S on the expressions of BDNF and p-TrkB protein in the hippocampus of CUMS-treated rat. Rats were exposed to CUMS for 2 w and then cotreated with NaHS (0.03 or 0.1 mmol/kg/day, i.p.) and CUMS for 2 w. Immunoblot was used to analyze and quantify the expressions of BDNF and p-TrkB in the hippocampus of rats, and β-actin was used as an internal control. Values were expressed as the mean ± SEM of three independent experiments. , versus control group; , versus CUMS-treated along group.
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