Hydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway

Figure 6

Effect of H₂S on depressive- and anxiety-like behaviors in CUMS-exposed rats. Rats were exposed to CUMS for 2 w and then cotreated with NaHS (0.03 or 0.1 mmol/kg/day, i.p.) and CUMS for 2 w. (a)-(b) The depressive-like behavior was evaluated using novelty-suppressed feeding test (NSFT). (c)–(e) The anxiety-like behavior was evaluated using elevated plus-maze (EPM) test. versus control group, , versus CUMS-treated alone group. , versus CUMS-treated group. Data represent group mean ± SEM (/group).

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