Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases

Figure 3

A network related to oxidative stress in age-related macular degeneration (AMD). An Agilent Literature Search was used as the basis for the network. We used 25 AMD-associated genes identified by GWAS as the target molecules and “oxidative stress” as the designated context in the Agilent Literature Search. The AMD-associated genes in the network are shown in yellow. The subnetworks containing potential therapeutic targets for AMD-related OS are enlarged in (a)–(d).