Thioredoxin-Interacting Protein Mediates NLRP3 Inflammasome Activation Involved in the Susceptibility to Ischemic Acute Kidney Injury in Diabetes

Table 1

General characteristics of the experimental animals before ischemia/reperfusion modeling.

	NS ()	NI/R ()	DS ()	DI/R ()	DI/R-RES ()
Blood glucose (mM)
Body weight (g)

The data in the table are means ± SE , versus NS group, and versus DS group.
NS and DS: nondiabetic and STZ-induced diabetic rats were subjected to sham operation. NI/R and DI/R: nondiabetic and STZ-induced diabetic rats were subjected to 25 min ischemia followed by 48 h reperfusion. DI/R-RES: STZ-induced diabetic rats that underwent I/R were treated with RES (10 mg/kg, ip daily) for 7 consecutive days before renal ischemia-reperfusion.