Endogenous Generation of Singlet Oxygen and Ozone in Human and Animal Tissues: Mechanisms, Biological Significance, and Influence of Dietary Components

Figure 8

Postulated conversion of linoleic acid 28 via dioxetanyl derivative 31 to major products 9-oxononanoic acid 32 and 4-hydroperoxy-2-nonenal 33 [49] or via dioxetanyl radical 38 to hydroperoxyaldehyde 33 and 8-oxooctanoic acid 39 [50]. Decomposition of the dioxetanyl derivatives affords excited carbonyls that transfer energy to O₂, thus forming ¹O₂. The asterisk indicates that the carbonyl is in excited state.