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Oxidative Medicine and Cellular Longevity
Volume 2016 (2016), Article ID 2481865, 17 pages
http://dx.doi.org/10.1155/2016/2481865
Research Article

Histone Deacetylase Inhibitors Increase p27Kip1 by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation

1Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, 80138 Naples, Italy
2Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Università degli Studi di Firenze, 50134 Firenze, Italy
3Dipartimento di Scienze Cardiotoraciche e Respiratorie, Seconda Università di Napoli, 80131 Napoli, Italy

Received 18 December 2014; Revised 2 August 2015; Accepted 9 August 2015

Academic Editor: Peter Backx

Copyright © 2016 Adriana Borriello et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Adriana Borriello, Silvio Naviglio, Debora Bencivenga, et al., “Histone Deacetylase Inhibitors Increase p27Kip1 by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation,” Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 2481865, 17 pages, 2016. doi:10.1155/2016/2481865