Nigella sativa Relieves the Altered Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats Fed with a High-Fat Diet

Figure 5

Effect of NSO, reference drugs, and I-OMe-AG538 on serum (a) or hepatic (b) TNF-α levels, gene expression ratio of ADAM-17/β-actin (c), and protein expressiom of TIMP-3 (d) in rats of all studied groups. The inset in (c) shows agarose gel electrophoresis of gene expression of ADAM-17 (157 bp) compared to β-actin (300 bp) (data are expressed as mean ± SE for 21 days of treatment, ). at .

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